Anti-ETS1 associated protein II抗體,ETS1相關(guān)蛋白2抗體
英文介紹:DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
此產(chǎn)品本公司有標(biāo)記的一抗出售,相關(guān)標(biāo)記有:Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記
注意事項:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品名稱:Anti-ETS1 associated protein II抗體,ETS1相關(guān)蛋白2抗體
產(chǎn)品編號:BYK-5164R
英文名稱:Anti-ETS1 associated protein II
中文名稱:ETS1相關(guān)蛋白2抗體
英文別名:EAP 2; EAP II; EAP2; EAPII; ETS 1 associated protein 2; ETS 1 associated protein II; ETS1 associated protein 2; ETS1-associated protein 2; ETS1-associated protein II; tdp2; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; TTRAP; TYDP2_HUMAN; Tyr DNA phosphodiesterase 2; Tyr-DNA phosphodiesterase 2; Tyrosyl DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; 5''-Tyr-DNA phosphodiesterase; 5''-tyrosyl-DNA phosphodiesterase; AD 022; AD022; MGC111021; MGC9099.
產(chǎn)品規(guī)格:0.1ml/0.2ml
此抗體本公司有單抗和多抗,可用于免疫組化(IHC),免疫印跡(WB),酶聯(lián)免疫(ELISA),IF、IP、流式細(xì)胞術(shù)等實驗(可來電索取說明)
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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Anti-ETS1 associated protein II抗體,ETS1相關(guān)蛋白2抗體封閉(Blocking):
轉(zhuǎn)膜完畢后,立即把蛋白膜放置到預(yù)先準(zhǔn)備好的Western洗滌液中,漂洗1-2分鐘,以洗去膜上的轉(zhuǎn)膜液。從轉(zhuǎn)膜完畢后所有的步驟,一定要注意膜的保濕,避免膜的干燥,否則極易產(chǎn)生較高的背景。
用微型臺式真空泵吸盡洗滌液,加入Western封閉液,在搖床上緩慢搖動,室溫封閉60分鐘。對于一些背景較高的抗體,可以在4℃ 封閉過夜。
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