美國BD公司Purified Mouse anti-TAZ抗體Clone M2-616
美國BD公司Purified Mouse anti-TAZ抗體Clone M2-616
規(guī)格
0.1 mg
貨號
560235
目錄價(jià)
¥ 5,543.00
Brand
BD Pharmingen™
Alternative Name
WWTR1
Concentration
0.5 mg/ml
Isotype
Mouse BALB/c IgG2b, κ
Reactivity
Human (QC Testing) Mouse (Tested in Development)
Application
Western blot (Routinely Tested)
Bioimaging (Tested During Development)
Immunogen
Human TAZ Recombinant Protein
Storage Buffer
Aqueous buffered solution containing ≤0.09% sodium azide.
詳細(xì)說明：
DESCRIPTION
Taz is a 49-kDa transcriptional co-activator with a PDZ-binding motif and is regulated by binding with 14-3-3 proteins. It plays a key role in differentiation of mesenchymal stem cells into either osteoblasts or adipocytes via interactions with key transcription factors Runx2 and PPAR γ . More recently, Taz was found to be a component of an E3 ubiquitin ligase involved in ubiquitin-dependent substrate proteolysis by mediating its interaction with the F-box protein β -Trcp. Therefore, Taz has dual functions of regulating protein degradation and transcription.
FORMAT
Format
Purified
SUGGESTED COMPANION PRODUCTS
| Cat No. | Description | Size | |
|---|---|---|---|
| 611449 | HeLa Cell Lysate RUO | 500 µg |
|
| 554656 | Stain Buffer (FBS) RUO | 500 mL |
|
| 554655 | Fixation Buffer RUO | 100 mL |
|
| 554723 | Perm/Wash Buffer RUO | 100 mL |
|
| 554002 | HRP Goat Anti-Mouse Ig RUO | 1 mL |
|
RESOURCES & TOOLS
- Download TDS
PREPARATION AND STORAGE
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C.
PRODUCT NOTICES
- Since applications vary, each investigator should titrate the reagent to obtain optimal results.
- Please refer to www.bdbiosciences。。ｃｏｍ/pharmingen/protocols for technical protocols.
- Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
- Triton is a trademark of the Dow Chemical Company.
- This antibody has been developed and certified for the bioimaging application. However, a routine bioimaging test is not performed on every lot. Researchers are encouraged to titrate the reagent for optimal performance.
