近紅外熒光染料用于生物成像時(shí)，除了具有近紅外吸收/發(fā)射波長、還熒光具有良好的水溶性和較低的生物毒性，特異的組織或細(xì)胞靶向性以及良好的細(xì)胞穿透性等，從而達(dá)到更安全、、靈敏的熒光成像目的。

為了提高近紅外熒光染料的水溶性和生物相容性和較低的生物毒性，可以將一種高分子聚合物材料-聚乙二醇（PEG）修飾到熒光染料上，常見的有CY3-PEG-MAL, Cy5-PEG-NH2,

Rhodamine B-PEG-NHS, CY7-PEG-COOH等等，經(jīng)過PEG修飾后的熒光染料還具有較長時(shí)間的體內(nèi)循環(huán)。

     DSPE-PEG2000-CY7這種近紅外染料鏈接PEG再鏈接二棕櫚酰磷脂酰乙醇胺，可以作為靶向材料作用于腫瘤。

DSPE-PEG2000-Cy7結(jié)構(gòu)式：

有些情況下，還可以將熒光分子修飾到生物分子、藥物以及納米載體表面，在研究生物分子功能、藥物分布和代謝、疾病尤其是腫瘤的診斷與治療中發(fā)揮有重要作用。

血清蛋白（BSA）是血漿中存在zui豐富的蛋白之一，它對內(nèi)生或外源性配體在血液中的運(yùn)輸、沉積起到重要作用。用BSA對近紅外熒光染料進(jìn)行修飾，不僅可以增加水溶性和生物相容性，還可 以提高它們的熒光強(qiáng)度。西安瑞禧生物科技有限公司常用的有CY3-BSA,

CY5-BSA，CY5.5-BSA，Streptavidin-CY5，Concanavalin A-CY5.5等等

為了提高對腫瘤等病灶的熒光成像檢測的靈敏性，可以將與腫瘤細(xì)胞中*的受體準(zhǔn)確結(jié)合的靶分子修飾到近紅外熒光染料上。當(dāng)用于腫瘤的診斷與治療時(shí)，有助于將染料分子靶向的送達(dá)腫瘤組織或細(xì)胞部位，提高成像時(shí)的特異性、靈敏性。目前常用的靶向分子包括如*、單克隆抗體和一些多肽分子等。例如，在許多的腫瘤組織中存在*受體過表達(dá)的現(xiàn)象，因此用*對近紅外熒光染料進(jìn)行表面修飾可使其能選擇性的富集于腫瘤組織中，特別適用于腫瘤的早期檢測。比如有CY5-PEG-FA  CY7-PEG-FA等等產(chǎn)品。

生物熒光成像：

近紅外熒光探針可對細(xì)胞或組織內(nèi)的一些重要物質(zhì)如活性氧（H2O2、氫氧自由基、單線態(tài)等）、活性氮（ONOO－、NO、NO+等）、硫醇、H2S、金屬離子（Cu2+、Zn2+、Hg2+等）、酶、pH等進(jìn)行檢測。

近紅外熒光染料也可以作為一種輔助手段修飾到藥物或藥物載體的表面，通過熒光成像的方法追蹤并檢測藥物在體內(nèi)的運(yùn)輸、釋放、分布，使這些過程可視化并利于進(jìn)行控制。例如將熒光分子與*用雙硫鍵連接，封裝于PEG-PLA納米粒中，由于腫瘤組織中富集的GSH能有效切斷雙硫鍵，使得熒光分子熒光增強(qiáng)，而*則用于殺死癌細(xì)胞，能同時(shí)實(shí)現(xiàn)靶向送藥和可視化檢測療效等多重目的。

西安瑞禧生物科技有限公司400種熒光相關(guān)產(chǎn)品列表：

CY3 

CY5 

CY7 

CY3-NHS   Cy3 NHS Ester

CY5-NHS   Cy5 NHS Ester

CY7-NHS   Cy7 NHS Ester

CY3-N3

CY5-N3

CY7-N3

CY3-MAL

CY5-MAL

CY7-MAL

CY3-COOH

CY5-COOH

CY7-COOH

DSPE-PEG-CY5 

DSPE-PEG-CY7  

FITC-PEG-NH2

FITC-PEG-COOH

FITC-PEG-MAL

FITC-PEG-NHS

FITC-PEG-Biotin

RB-PEG-NH2

RB-PEG-COOH

RB-PEG-MAL

RB-PEG-NHS

RB-PEG-Biotin

CY3-PEG-NH2

CY3-PEG-COOH

CY3-PEG-MAL

CY3-PEG-NHS

CY3-PEG-Biotin

CY5-PEG-NH2

CY5-PEG-COOH

CY5-PEG-MAL

CY5-PEG-NHS

CY5-PEG-Biotin

FITC-Poly-L-lysine

FITC-PLL

FITC-dextran

FITC-CM-dextran

TRITC-dextran

BSA-FITC

BSA-TRITC

FITC-Hyaluronic acid

BSA-FITC

Concanavalin A-CY5

Concanavalin A-Biotin

Concanavalin A-SH

Concanavalin A-TRITC

Streptavidin-SH

FITC-Streptavidin

CY5.5-Streptavidin

CY5-Streptavidin

HSA-FITC

HSA-TRITC

HSA-Biotin

BSA-TRITC

Concanavalin A-Sepharose

Concanavalin A-CY3

Avidin-CY3

Avidin-CY5

Avidin-CY5.5

Avidin

Avidin-Sepharose

Avidin-thiol

Avidin-FITC

Avidin-TRITC

Rhodamine B-Hyaluronic acid

6-Carboxy Fluorescein; 6-FAM

5(6)Carboxy fluorescein; 5(6)-FAM

5-Carboxyfluorescein succinimidyl ester; 5-FAM, SE

5-Carboxytetramethylrhodamine; 5-TAMRA

5(6)-Carboxytetramethylrhodamine succinimidyl ester;5(6)-TAMRA, SE

5-Carboxy-X-rhodamine; 5-ROX

6-Carboxy-X-rhodamine; 6-ROX

5(6)-Carboxy-X-rhodamine; 5(6)-ROX

5(6)-Aminofluorescein

5(6)-Carboxyfluorescein diacetate

5-Aminofluorescein

Fluorescein isothiocyanate

AMCA Alkyne

AMCA Azide

DBCO-Cy3

DBCO-Cy5

5-FAM Alkyne

5-FAM Azide

6-Carboxy-X-Rhodamine，SE (NHS) 6-羧基-X-羅丹明琥珀酰亞胺酯

5-TAMRA-Osu   5-羧基四甲基羅丹明琥珀酰亞胺酯

Streptavidin-CY5.5

Streptavidin-CY5

Streptavidin-CY3

Streptavidin-TRITC

Streptavidin-FITC

Streptavidin-thiol

Avidin-CY3

Avidin-CY5

Avidin-CY5.5

Avidin (without modification) 

Avidin-Sepharose

Avidin-thiol

Avidin-FITC

Avidin-TRITC

Human serum albumin, Sepharose beads （HAS- Sepharose beads）

Human serum albumin thiol (HSA-SH)

Human serum albumin Biotin (HSA-Biotin)

Human serum albumin TRITC (HSA-TRITC)

Human serum albumin Fluorescein (HSA-FITC)

Human serum albumin CY5 (HSA-CY5)

Human serum albumin CY3 (HSA-CY3)

Human serum albumin CY5.5 (HSA-CY5.5)

Human serum albumin (HSA, without modification)

Bovine serum albumin, Sepharose beads （BSA- Sepharose beads）

Bovine serum albumin thiol (BSA-SH)

Bovine serum albumin Biotin (BSA-Biotin)

Bovine serum albumin TRITC (BSA-TRITC)

Bovine serum albumin Fluorescein (BSA-FITC)

Bovine serum albumin CY5 (BSA-CY5)

Bovine serum albumin CY3 (BSA-CY3)

Bovine serum albumin CY5.5 (BSA-CY5.5)

Bovine serum albumin (BSA, without modification)

Bovine serum albumin tetramethylrhodamine (BSA-tetramethylrhodamine)

Concanavalin A刀豆求蛋白A產(chǎn)品：

Concanavalin A-CY5

Concanavalin A-CY3

Concanavalin A-CY5.5

Concanavalin A-Sepharose

Concanavalin A-Biotin

Concanavalin A-SH

Concanavalin A-tetramethylrhodamine

Concanavalin A-FITC

Concanavalin A (without modification)

Ficoll-Fluorescein, MW 20 kDa

Ficoll-Fluorescein, MW 40 kDa

Ficoll-Fluorescein, MW 70 kDa

Ficoll-Fluorescein, MW 400 kDa

Heparin-Biotin, MW 18 kDa

Heparin-Rhodamine, MW 18 kDa

Heparin-Fluorescein, MW 18 kDa

Heparin-NIR Dye, HP MW: 18kDa

Heparin-Amine, MW 18 kDa

Chitosan-Rhodamine, 200-500 cP, 85% DDA

Chitosan-Rhodamine, MW 200kDa, 95% DDA

Chitosan-Rhodamine, MW 200kDa, 85% DDA

Chitosan-Fluorescein, 10-50 cP, 85% DDA

Chitosan-Fluorescein, 200-500 cP, 85% DDA

Chitosan-Fluorescein, MW 200kDa, 95% DDA

Chitosan-Fluorescein, MW 200kDa, 85% DDA

Dextran-Biotin, MW 6 kDa

Dextran-Biotin, MW 20 kDa

Dextran-Biotin, MW 40 kDa

Dextran-Biotin, MW 70 kDa

Dextran-Biotin, MW 100 kDa

Dextran-Biotin, MW 550 kDa

Dextran-Biotin, MW 2,000 kDa

Dextran-Rhodamine, MW 6 kDa

Dextran-Rhodamine, MW 20 kDa

Dextran-Rhodamine, MW 40 kDa

Dextran-Rhodamine, MW 70 kDa

Dextran-Rhodamine, MW 100 kDa

Dextran-Rhodamine, MW 550 kDa

Dextran-Rhodamine, MW 2,000 kDa

Dextran-Fluorescein, MW 6 kDa

Dextran-Fluorescein, MW 20 kDa

Dextran-Fluorescein, MW 40 kDa

Dextran-Fluorescein, MW 70 kDa

Dextran-Fluorescein, MW 100 kDa

Dextran-Fluorescein, MW 550 kDa

Dextran-Fluorescein, MW 2,000 kDa

Dextran-NIR Dye, DE MW: 6k-2000k

Dextran-Amine, MW 6 kDa

Dextran-Amine, MW 20 kDa

Dextran-Amine, MW 40 kDa

Dextran-Amine, MW 70 kDa

Dextran-Amine, MW 100 kDa

Dextran-Amine, MW 550 kDa

Dextran-Amine, MW 2,000 kDa

FITC-DEAE-dextrans熒光素葡聚糖產(chǎn)品：

FITC-DEAE-dextran,MW:3000-6000

FITC-DEAE-dextran,MW:20000-30000

FITC-DEAE-dextran,MW:30000-60000

FITC-DEAE-dextran,MW:70000-90000

FITC-DEAE-dextran,MW:160000-190000

FITC-Inulin熒光素菊粉產(chǎn)品：

FITC-Inulin,MW:4000

FITC-Polysucrose熒光素聚蔗糖產(chǎn)品：

FITC-Polysucrose,MW:15000-30000

FITC-Polysucrose,MW:30000-50000

FITC-Polysucrose,MW:70000

FITC-Polysucrose,MW:300000-450000

FITC-CM-Polysucrose 熒光素羧基聚蔗糖產(chǎn)品：

FITC-CM-Polysucrose,MW:60000-80000

FITC-CM-Polysucrose,MW:350000-450000

FITC-DEAE-Polysucrose熒光素DEAE聚蔗糖產(chǎn)品：

FITC-DEAE-Polysucrose,MW:400000

FITC-Dextran sulfate產(chǎn)品：

FITC-Dextran sulphate,MW:30000-50000

FITC-Dextran sulphate,MW:400000-650000

CY3-Dextran, CY5-Dextran，CY7-Dextran產(chǎn)品列表：

DX5-S3-1      Dextran, Cy3 labeled     5000 Da     2 mg 

DX10-S3-1     Dextran, Cy3 labeled     10000 Da         5 mg 

DX40-S3-1     Dextran, Cy3 labeled     40000 Da   5 mg

Thiol Dextran產(chǎn)品列表:

DX5-TH-1      Dextran, Thiol Functional     5000 Da  50 mg    

DX10-TH-1    Dextran, Thiol Functional     10000 Da       50 mg    

DX40-TH-1    Dextran, Thiol Functional     40000 Da       50 mg    

Wheat germ agglutinin & Conjugates（麥胚凝集素交聯(lián)劑）

FITC-Wheat germ agglutinin

RB-Wheat germ agglutinin

CY3-Wheat germ agglutinin

CY5-Wheat germ agglutinin

Transferrin & Conjugates（熒光標(biāo)記轉(zhuǎn)染鐵蛋白）

FITC-Transferrin

RB-Transferrin

CY3-Transferrin

CY5-Transferrin

CY7-Transferrin

Biotin-Transferrin

Lysozyme & conjugates（熒光標(biāo)記*）

FITC-Lysozyme

RB-Lysozyme

CY3-Lysozyme

CY5-Lysozyme

CY7-Lysozyme

Biotin-Lysozyme

Catalase conjugates（熒光標(biāo)記過氧化氫酶）

FITC-Catalase

RB-Catalase

CY3-Catalase

CY5-Catalase

CY7-Catalase

Biotin-Catalase

Polylysine conjugates（熒光標(biāo)記多聚賴氨酸氨酸）

FITC-Polylysine

RB-Polylysine

CY3-Polylysine

CY5-Polylysine

CY7-Polylysine

Biotin-Polylysine

Protein A & conjugates（熒光標(biāo)記蛋白A）

FITC-Protein A

RB-Protein A

CY3-Protein A

CY5-Protein A

CY7-Protein A

Biotin-Protein A

HRP-Protein A

Maleimide-Protein A

Insulin & conjugates(熒光標(biāo)記胰島素)

FITC-Insulin

RB-Insulin

CY3-Insulin

CY5-Insulin

Biotin-Insulin

Horseradish Peroxidase (HRP) Conjugates（辣根過氧化物酶交聯(lián)劑）

Biotin-HRP

Streptavidin-HRP

FITC-HRP

CY3-HRP

CY5-HRP

RB-HRP

Maleimide-HRP

NH2-HRP

HS-HRP

Hylauronic acid & Conjugates（透明質(zhì)酸交聯(lián)劑）

FITC-Hylauronic acid

RB-Hylauronic acid

CY3-Hylauronic acid

CY5-Hylauronic acid

CY7-Hylauronic acid

Biotin-Hylauronic acid

Heparin & Conjugates（肝素交聯(lián)劑）

FITC-Heparin

RB-Heparin

CY3-Heparin

CY5-Heparin

Biotin-Heparin

Ficoll & Conjugates（聚蔗糖交聯(lián)劑）

FITC-Ficoll

RB-Ficoll

CY3-Ficoll

CY5-Ficoll

Biotin-Ficoll

Chitosan & Conjugates（殼聚糖交聯(lián)劑）

FITC-Chitosan

RB-Chitosan

CY3-Chitosan

CY5-Chitosan

Biotin-Chitosan

Lipopolysaccharides Conjugates（脂多糖交聯(lián)）

FITC-Lipopolysaccharides

RB-Lipopolysaccharides

CY3-Lipopolysaccharides

CY5-Lipopolysaccharides

CY5.5-Lipopolysaccharides

Casein conjugates（酪蛋白交聯(lián)劑）

FITC-Casein

RB-Casein

CY3-Casein

CY5-Casein

CY5.5-Casein

Biotin-Casein

α-Chymotrypsin conjugates （α-胰凝乳蛋白交聯(lián)劑）

FITC-α-Chymotrypsin

RB-α-Chymotrypsin

CY3-α-Chymotrypsin

CY5-α-Chymotrypsin

CY5.5-α-Chymotrypsin

Polylysine & conjugates（多聚賴氨酸和共軛物）

FITC-Polylysine

RB-Polylysine

CY3-Polylysine

CY5-Polylysine

CY5.5-Polylysine

Biotin-Polylysine

C10B0            Cyanine3 alkyne, 10 mg

C1030            Cyanine3 azide, 10 mg

21090             Cyanine3 carboxylic acid, 5 mg

21070             Cyanine3 hydrazide, 5 mg

21080             Cyanine3 maleimide, 5 mg

21020             Cyanine3 NHS ester, 5 mg

41020             Cyanine3 NHS ester, 25 mg

B2030            Cyanine3.5 azide, 5 mg

42090             Cyanine3.5 carboxylic acid, 25 mg

52020             Cyanine3.5 NHS ester, 50 mg

B30B0            Cyanine5 alkyne, 5 mg

230C0            Cyanine5 amine, 5 mg

C3030            Cyanine5 azide, 10 mg

430A0            Cyanine5 Boc-hydrazide, 25 mg

43090             Cyanine5 carboxylic acid, 25 mg

23070             Cyanine5 hydrazide, 5 mg

43080             Cyanine5 maleimide, 25 mg

23020             Cyanine5 NHS ester, 5 mg

B70B0            Cyanine5.5 alkyne, 5 mg

B4030            Cyanine5.5 azide, 5 mg

27090             Cyanine5.5 carboxylic acid, 5 mg

57080             Cyanine5.5 maleimide, 50 mg

27020             Cyanine5.5 NHS ester, 5 mg

450C0            Cyanine7 amine, 25 mg

B5030            Cyanine7 azide, 5 mg

45090             Cyanine7 carboxylic acid, 25 mg

25080             Cyanine7 maleimide, 5 mg

25020             Cyanine7 NHS ester, 5 mg

260C0            Cyanine7.5 amine, 5 mg

B6030            Cyanine7.5 azide, 5 mg

26090             Cyanine7.5 carboxylic acid, 5 mg

26080             Cyanine7.5 maleimide, 5 mg

26020             Cyanine7.5 NHS ester, 5 mg

23320             Sulfo-Cyanine 5 NHS ester, 5 mg

B1330            Sulfo-Cyanine3 azide, 5 mg

21390             Sulfo-Cyanine3 carboxylic acid, 5 mg

21380             Sulfo-Cyanine3 maleimide, 5 mg

21320             Sulfo-Cyanine3 NHS ester, 5 mg

B33B0            Sulfo-Cyanine5 alkyne, 5 mg

B3330            Sulfo-Cyanine5 azide, 5 mg

23390             Sulfo-Cyanine5 carboxylic acid, 5 mg

23380             Sulfo-Cyanine5 maleimide, 5 mg

B5330            Sulfo-Cyanine7 azide, 5 mg

25390             Sulfo-Cyanine7 carboxylic acid, 5 mg

45320             Sulfo-Cyanine7 NHS ester, 25 mg

近紅外熒光染料用于生物成像時(shí)，除了具有近紅外吸收/發(fā)射波長、還熒光具有良好的水溶性和較低的生物毒性，特異的組織或細(xì)胞靶向性以及良好的細(xì)胞穿透性等，從而達(dá)到更安全、、靈敏的熒光成像目的。

為了提高近紅外熒光染料的水溶性和生物相容性和較低的生物毒性，可以將一種高分子聚合物材料-聚乙二醇（PEG）修飾到熒光染料上，常見的有CY3-PEG-MAL, Cy5-PEG-NH2,

Rhodamine B-PEG-NHS, CY7-PEG-COOH等等，經(jīng)過PEG修飾后的熒光染料還具有較長時(shí)間的體內(nèi)循環(huán)。

     DSPE-PEG2000-CY7這種近紅外染料鏈接PEG再鏈接二棕櫚酰磷脂酰乙醇胺，可以作為靶向材料作用于腫瘤。

DSPE-PEG2000-Cy7結(jié)構(gòu)式：

有些情況下，還可以將熒光分子修飾到生物分子、藥物以及納米載體表面，在研究生物分子功能、藥物分布和代謝、疾病尤其是腫瘤的診斷與治療中發(fā)揮有重要作用。

血清蛋白（BSA）是血漿中存在zui豐富的蛋白之一，它對內(nèi)生或外源性配體在血液中的運(yùn)輸、沉積起到重要作用。用BSA對近紅外熒光染料進(jìn)行修飾，不僅可以增加水溶性和生物相容性，還可 以提高它們的熒光強(qiáng)度。西安瑞禧生物科技有限公司常用的有CY3-BSA,

CY5-BSA，CY5.5-BSA，Streptavidin-CY5，Concanavalin A-CY5.5等等

為了提高對腫瘤等病灶的熒光成像檢測的靈敏性，可以將與腫瘤細(xì)胞中*的受體準(zhǔn)確結(jié)合的靶分子修飾到近紅外熒光染料上。當(dāng)用于腫瘤的診斷與治療時(shí)，有助于將染料分子靶向的送達(dá)腫瘤組織或細(xì)胞部位，提高成像時(shí)的特異性、靈敏性。目前常用的靶向分子包括如*、單克隆抗體和一些多肽分子等。例如，在許多的腫瘤組織中存在*受體過表達(dá)的現(xiàn)象，因此用*對近紅外熒光染料進(jìn)行表面修飾可使其能選擇性的富集于腫瘤組織中，特別適用于腫瘤的早期檢測。比如有CY5-PEG-FA  CY7-PEG-FA等等產(chǎn)品。

生物熒光成像：

近紅外熒光探針可對細(xì)胞或組織內(nèi)的一些重要物質(zhì)如活性氧（H2O2、氫氧自由基、單線態(tài)等）、活性氮（ONOO－、NO、NO+等）、硫醇、H2S、金屬離子（Cu2+、Zn2+、Hg2+等）、酶、pH等進(jìn)行檢測。

近紅外熒光染料也可以作為一種輔助手段修飾到藥物或藥物載體的表面，通過熒光成像的方法追蹤并檢測藥物在體內(nèi)的運(yùn)輸、釋放、分布，使這些過程可視化并利于進(jìn)行控制。例如將熒光分子與*用雙硫鍵連接，封裝于PEG-PLA納米粒中，由于腫瘤組織中富集的GSH能有效切斷雙硫鍵，使得熒光分子熒光增強(qiáng)，而*則用于殺死癌細(xì)胞，能同時(shí)實(shí)現(xiàn)靶向送藥和可視化檢測療效等多重目的。

西安瑞禧生物科技有限公司400種熒光相關(guān)產(chǎn)品列表：

CY3 

CY5 

CY7 

CY3-NHS   Cy3 NHS Ester

CY5-NHS   Cy5 NHS Ester

CY7-NHS   Cy7 NHS Ester

CY3-N3

CY5-N3

CY7-N3

CY3-MAL

CY5-MAL

CY7-MAL

CY3-COOH

CY5-COOH

CY7-COOH

DSPE-PEG-CY5 

DSPE-PEG-CY7  

FITC-PEG-NH2

FITC-PEG-COOH

FITC-PEG-MAL

FITC-PEG-NHS

FITC-PEG-Biotin

RB-PEG-NH2

RB-PEG-COOH

RB-PEG-MAL

RB-PEG-NHS

RB-PEG-Biotin

CY3-PEG-NH2

CY3-PEG-COOH

CY3-PEG-MAL

CY3-PEG-NHS

CY3-PEG-Biotin

CY5-PEG-NH2

CY5-PEG-COOH

CY5-PEG-MAL

CY5-PEG-NHS

CY5-PEG-Biotin

FITC-Poly-L-lysine

FITC-PLL

FITC-dextran

FITC-CM-dextran

TRITC-dextran

BSA-FITC

BSA-TRITC

FITC-Hyaluronic acid

BSA-FITC

Concanavalin A-CY5

Concanavalin A-Biotin

Concanavalin A-SH

Concanavalin A-TRITC

Streptavidin-SH

FITC-Streptavidin

CY5.5-Streptavidin

CY5-Streptavidin

HSA-FITC

HSA-TRITC

HSA-Biotin

BSA-TRITC

Concanavalin A-Sepharose

Concanavalin A-CY3

Avidin-CY3

Avidin-CY5

Avidin-CY5.5

Avidin

Avidin-Sepharose

Avidin-thiol

Avidin-FITC

Avidin-TRITC

Rhodamine B-Hyaluronic acid

6-Carboxy Fluorescein; 6-FAM

5(6)Carboxy fluorescein; 5(6)-FAM

5-Carboxyfluorescein succinimidyl ester; 5-FAM, SE

5-Carboxytetramethylrhodamine; 5-TAMRA

5(6)-Carboxytetramethylrhodamine succinimidyl ester;5(6)-TAMRA, SE

5-Carboxy-X-rhodamine; 5-ROX

6-Carboxy-X-rhodamine; 6-ROX

5(6)-Carboxy-X-rhodamine; 5(6)-ROX

5(6)-Aminofluorescein

5(6)-Carboxyfluorescein diacetate

5-Aminofluorescein

Fluorescein isothiocyanate

AMCA Alkyne

AMCA Azide

DBCO-Cy3

DBCO-Cy5

5-FAM Alkyne

5-FAM Azide

6-Carboxy-X-Rhodamine，SE (NHS) 6-羧基-X-羅丹明琥珀酰亞胺酯

5-TAMRA-Osu   5-羧基四甲基羅丹明琥珀酰亞胺酯

Streptavidin-CY5.5

Streptavidin-CY5

Streptavidin-CY3

Streptavidin-TRITC

Streptavidin-FITC

Streptavidin-thiol

Avidin-CY3

Avidin-CY5

Avidin-CY5.5

Avidin (without modification) 

Avidin-Sepharose

Avidin-thiol

Avidin-FITC

Avidin-TRITC

Human serum albumin, Sepharose beads （HAS- Sepharose beads）

Human serum albumin thiol (HSA-SH)

Human serum albumin Biotin (HSA-Biotin)

Human serum albumin TRITC (HSA-TRITC)

Human serum albumin Fluorescein (HSA-FITC)

Human serum albumin CY5 (HSA-CY5)

Human serum albumin CY3 (HSA-CY3)

Human serum albumin CY5.5 (HSA-CY5.5)

Human serum albumin (HSA, without modification)

Bovine serum albumin, Sepharose beads （BSA- Sepharose beads）

Bovine serum albumin thiol (BSA-SH)

Bovine serum albumin Biotin (BSA-Biotin)

Bovine serum albumin TRITC (BSA-TRITC)

Bovine serum albumin Fluorescein (BSA-FITC)

Bovine serum albumin CY5 (BSA-CY5)

Bovine serum albumin CY3 (BSA-CY3)

Bovine serum albumin CY5.5 (BSA-CY5.5)

Bovine serum albumin (BSA, without modification)

Bovine serum albumin tetramethylrhodamine (BSA-tetramethylrhodamine)

Concanavalin A刀豆求蛋白A產(chǎn)品：

Concanavalin A-CY5

Concanavalin A-CY3

Concanavalin A-CY5.5

Concanavalin A-Sepharose

Concanavalin A-Biotin

Concanavalin A-SH

Concanavalin A-tetramethylrhodamine

Concanavalin A-FITC

Concanavalin A (without modification)

Ficoll-Fluorescein, MW 20 kDa

Ficoll-Fluorescein, MW 40 kDa

Ficoll-Fluorescein, MW 70 kDa

Ficoll-Fluorescein, MW 400 kDa

Heparin-Biotin, MW 18 kDa

Heparin-Rhodamine, MW 18 kDa

Heparin-Fluorescein, MW 18 kDa

Heparin-NIR Dye, HP MW: 18kDa

Heparin-Amine, MW 18 kDa

Chitosan-Rhodamine, 200-500 cP, 85% DDA

Chitosan-Rhodamine, MW 200kDa, 95% DDA

Chitosan-Rhodamine, MW 200kDa, 85% DDA

Chitosan-Fluorescein, 10-50 cP, 85% DDA

Chitosan-Fluorescein, 200-500 cP, 85% DDA

Chitosan-Fluorescein, MW 200kDa, 95% DDA

Chitosan-Fluorescein, MW 200kDa, 85% DDA

Dextran-Biotin, MW 6 kDa

Dextran-Biotin, MW 20 kDa

Dextran-Biotin, MW 40 kDa

Dextran-Biotin, MW 70 kDa

Dextran-Biotin, MW 100 kDa

Dextran-Biotin, MW 550 kDa

Dextran-Biotin, MW 2,000 kDa

Dextran-Rhodamine, MW 6 kDa

Dextran-Rhodamine, MW 20 kDa

Dextran-Rhodamine, MW 40 kDa

Dextran-Rhodamine, MW 70 kDa

Dextran-Rhodamine, MW 100 kDa

Dextran-Rhodamine, MW 550 kDa

Dextran-Rhodamine, MW 2,000 kDa

Dextran-Fluorescein, MW 6 kDa

Dextran-Fluorescein, MW 20 kDa

Dextran-Fluorescein, MW 40 kDa

Dextran-Fluorescein, MW 70 kDa

Dextran-Fluorescein, MW 100 kDa

Dextran-Fluorescein, MW 550 kDa

Dextran-Fluorescein, MW 2,000 kDa

Dextran-NIR Dye, DE MW: 6k-2000k

Dextran-Amine, MW 6 kDa

Dextran-Amine, MW 20 kDa

Dextran-Amine, MW 40 kDa

Dextran-Amine, MW 70 kDa

Dextran-Amine, MW 100 kDa

Dextran-Amine, MW 550 kDa

Dextran-Amine, MW 2,000 kDa

FITC-DEAE-dextrans熒光素葡聚糖產(chǎn)品：

FITC-DEAE-dextran,MW:3000-6000

FITC-DEAE-dextran,MW:20000-30000

FITC-DEAE-dextran,MW:30000-60000

FITC-DEAE-dextran,MW:70000-90000

FITC-DEAE-dextran,MW:160000-190000

FITC-Inulin熒光素菊粉產(chǎn)品：

FITC-Inulin,MW:4000

FITC-Polysucrose熒光素聚蔗糖產(chǎn)品：

FITC-Polysucrose,MW:15000-30000

FITC-Polysucrose,MW:30000-50000

FITC-Polysucrose,MW:70000

FITC-Polysucrose,MW:300000-450000

FITC-CM-Polysucrose 熒光素羧基聚蔗糖產(chǎn)品：

FITC-CM-Polysucrose,MW:60000-80000

FITC-CM-Polysucrose,MW:350000-450000

FITC-DEAE-Polysucrose熒光素DEAE聚蔗糖產(chǎn)品：

FITC-DEAE-Polysucrose,MW:400000

FITC-Dextran sulfate產(chǎn)品：

FITC-Dextran sulphate,MW:30000-50000

FITC-Dextran sulphate,MW:400000-650000

CY3-Dextran, CY5-Dextran，CY7-Dextran產(chǎn)品列表：

DX5-S3-1      Dextran, Cy3 labeled     5000 Da     2 mg 

DX10-S3-1     Dextran, Cy3 labeled     10000 Da         5 mg 

DX40-S3-1     Dextran, Cy3 labeled     40000 Da   5 mg

Thiol Dextran產(chǎn)品列表:

DX5-TH-1      Dextran, Thiol Functional     5000 Da  50 mg    

DX10-TH-1    Dextran, Thiol Functional     10000 Da       50 mg    

DX40-TH-1    Dextran, Thiol Functional     40000 Da       50 mg    

Wheat germ agglutinin & Conjugates（麥胚凝集素交聯(lián)劑）

FITC-Wheat germ agglutinin

RB-Wheat germ agglutinin

CY3-Wheat germ agglutinin

CY5-Wheat germ agglutinin

Transferrin & Conjugates（熒光標(biāo)記轉(zhuǎn)染鐵蛋白）

FITC-Transferrin

RB-Transferrin

CY3-Transferrin

CY5-Transferrin

CY7-Transferrin

Biotin-Transferrin

Lysozyme & conjugates（熒光標(biāo)記*）

FITC-Lysozyme

RB-Lysozyme

CY3-Lysozyme

CY5-Lysozyme

CY7-Lysozyme

Biotin-Lysozyme

Catalase conjugates（熒光標(biāo)記過氧化氫酶）

FITC-Catalase

RB-Catalase

CY3-Catalase

CY5-Catalase

CY7-Catalase

Biotin-Catalase

Polylysine conjugates（熒光標(biāo)記多聚賴氨酸氨酸）

FITC-Polylysine

RB-Polylysine

CY3-Polylysine

CY5-Polylysine

CY7-Polylysine

Biotin-Polylysine

Protein A & conjugates（熒光標(biāo)記蛋白A）

FITC-Protein A

RB-Protein A

CY3-Protein A

CY5-Protein A

CY7-Protein A

Biotin-Protein A

HRP-Protein A

Maleimide-Protein A

Insulin & conjugates(熒光標(biāo)記胰島素)

FITC-Insulin

RB-Insulin

CY3-Insulin

CY5-Insulin

Biotin-Insulin

Horseradish Peroxidase (HRP) Conjugates（辣根過氧化物酶交聯(lián)劑）

Biotin-HRP

Streptavidin-HRP

FITC-HRP

CY3-HRP

CY5-HRP

RB-HRP

Maleimide-HRP

NH2-HRP

HS-HRP

Hylauronic acid & Conjugates（透明質(zhì)酸交聯(lián)劑）

FITC-Hylauronic acid

RB-Hylauronic acid

CY3-Hylauronic acid

CY5-Hylauronic acid

CY7-Hylauronic acid

Biotin-Hylauronic acid

Heparin & Conjugates（肝素交聯(lián)劑）

FITC-Heparin

RB-Heparin

CY3-Heparin

CY5-Heparin

Biotin-Heparin

Ficoll & Conjugates（聚蔗糖交聯(lián)劑）

FITC-Ficoll

RB-Ficoll

CY3-Ficoll

CY5-Ficoll

Biotin-Ficoll

Chitosan & Conjugates（殼聚糖交聯(lián)劑）

FITC-Chitosan

RB-Chitosan

CY3-Chitosan

CY5-Chitosan

Biotin-Chitosan

Lipopolysaccharides Conjugates（脂多糖交聯(lián)）

FITC-Lipopolysaccharides

RB-Lipopolysaccharides

CY3-Lipopolysaccharides

CY5-Lipopolysaccharides

CY5.5-Lipopolysaccharides

Casein conjugates（酪蛋白交聯(lián)劑）

FITC-Casein

RB-Casein

CY3-Casein

CY5-Casein

CY5.5-Casein

Biotin-Casein

α-Chymotrypsin conjugates （α-胰凝乳蛋白交聯(lián)劑）

FITC-α-Chymotrypsin

RB-α-Chymotrypsin

CY3-α-Chymotrypsin

CY5-α-Chymotrypsin

CY5.5-α-Chymotrypsin

Polylysine & conjugates（多聚賴氨酸和共軛物）

FITC-Polylysine

RB-Polylysine

CY3-Polylysine

CY5-Polylysine

CY5.5-Polylysine

Biotin-Polylysine

C10B0            Cyanine3 alkyne, 10 mg

C1030            Cyanine3 azide, 10 mg

21090             Cyanine3 carboxylic acid, 5 mg

21070             Cyanine3 hydrazide, 5 mg

21080             Cyanine3 maleimide, 5 mg

21020             Cyanine3 NHS ester, 5 mg

41020             Cyanine3 NHS ester, 25 mg

B2030            Cyanine3.5 azide, 5 mg

42090             Cyanine3.5 carboxylic acid, 25 mg

52020             Cyanine3.5 NHS ester, 50 mg

B30B0            Cyanine5 alkyne, 5 mg

230C0            Cyanine5 amine, 5 mg

C3030            Cyanine5 azide, 10 mg

430A0            Cyanine5 Boc-hydrazide, 25 mg

43090             Cyanine5 carboxylic acid, 25 mg

23070             Cyanine5 hydrazide, 5 mg

43080             Cyanine5 maleimide, 25 mg

23020             Cyanine5 NHS ester, 5 mg

B70B0            Cyanine5.5 alkyne, 5 mg

B4030            Cyanine5.5 azide, 5 mg

27090             Cyanine5.5 carboxylic acid, 5 mg

57080             Cyanine5.5 maleimide, 50 mg

27020             Cyanine5.5 NHS ester, 5 mg

450C0            Cyanine7 amine, 25 mg

B5030            Cyanine7 azide, 5 mg

45090             Cyanine7 carboxylic acid, 25 mg

25080             Cyanine7 maleimide, 5 mg

25020             Cyanine7 NHS ester, 5 mg

260C0            Cyanine7.5 amine, 5 mg

B6030            Cyanine7.5 azide, 5 mg

26090             Cyanine7.5 carboxylic acid, 5 mg

26080             Cyanine7.5 maleimide, 5 mg

26020             Cyanine7.5 NHS ester, 5 mg

23320             Sulfo-Cyanine 5 NHS ester, 5 mg

B1330            Sulfo-Cyanine3 azide, 5 mg

21390             Sulfo-Cyanine3 carboxylic acid, 5 mg

21380             Sulfo-Cyanine3 maleimide, 5 mg

21320             Sulfo-Cyanine3 NHS ester, 5 mg

B33B0            Sulfo-Cyanine5 alkyne, 5 mg

B3330            Sulfo-Cyanine5 azide, 5 mg

23390             Sulfo-Cyanine5 carboxylic acid, 5 mg

23380             Sulfo-Cyanine5 maleimide, 5 mg

B5330            Sulfo-Cyanine7 azide, 5 mg

25390             Sulfo-Cyanine7 carboxylic acid, 5 mg

45320             Sulfo-Cyanine7 NHS ester, 25 mg

近紅外熒光染料用于生物成像時(shí)，除了具有近紅外吸收/發(fā)射波長、還熒光具有良好的水溶性和較低的生物毒性，特異的組織或細(xì)胞靶向性以及良好的細(xì)胞穿透性等，從而達(dá)到更安全、、靈敏的熒光成像目的。

為了提高近紅外熒光染料的水溶性和生物相容性和較低的生物毒性，可以將一種高分子聚合物材料-聚乙二醇（PEG）修飾到熒光染料上，常見的有CY3-PEG-MAL, Cy5-PEG-NH2,

Rhodamine B-PEG-NHS, CY7-PEG-COOH等等，經(jīng)過PEG修飾后的熒光染料還具有較長時(shí)間的體內(nèi)循環(huán)。

     DSPE-PEG2000-CY7這種近紅外染料鏈接PEG再鏈接二棕櫚酰磷脂酰乙醇胺，可以作為靶向材料作用于腫瘤。

DSPE-PEG2000-Cy7結(jié)構(gòu)式：

有些情況下，還可以將熒光分子修飾到生物分子、藥物以及納米載體表面，在研究生物分子功能、藥物分布和代謝、疾病尤其是腫瘤的診斷與治療中發(fā)揮有重要作用。

血清蛋白（BSA）是血漿中存在zui豐富的蛋白之一，它對內(nèi)生或外源性配體在血液中的運(yùn)輸、沉積起到重要作用。用BSA對近紅外熒光染料進(jìn)行修飾，不僅可以增加水溶性和生物相容性，還可 以提高它們的熒光強(qiáng)度。西安瑞禧生物科技有限公司常用的有CY3-BSA,

CY5-BSA，CY5.5-BSA，Streptavidin-CY5，Concanavalin A-CY5.5等等

為了提高對腫瘤等病灶的熒光成像檢測的靈敏性，可以將與腫瘤細(xì)胞中*的受體準(zhǔn)確結(jié)合的靶分子修飾到近紅外熒光染料上。當(dāng)用于腫瘤的診斷與治療時(shí)，有助于將染料分子靶向的送達(dá)腫瘤組織或細(xì)胞部位，提高成像時(shí)的特異性、靈敏性。目前常用的靶向分子包括如*、單克隆抗體和一些多肽分子等。例如，在許多的腫瘤組織中存在*受體過表達(dá)的現(xiàn)象，因此用*對近紅外熒光染料進(jìn)行表面修飾可使其能選擇性的富集于腫瘤組織中，特別適用于腫瘤的早期檢測。比如有CY5-PEG-FA  CY7-PEG-FA等等產(chǎn)品。

生物熒光成像：

近紅外熒光探針可對細(xì)胞或組織內(nèi)的一些重要物質(zhì)如活性氧（H2O2、氫氧自由基、單線態(tài)等）、活性氮（ONOO－、NO、NO+等）、硫醇、H2S、金屬離子（Cu2+、Zn2+、Hg2+等）、酶、pH等進(jìn)行檢測。

近紅外熒光染料也可以作為一種輔助手段修飾到藥物或藥物載體的表面，通過熒光成像的方法追蹤并檢測藥物在體內(nèi)的運(yùn)輸、釋放、分布，使這些過程可視化并利于進(jìn)行控制。例如將熒光分子與*用雙硫鍵連接，封裝于PEG-PLA納米粒中，由于腫瘤組織中富集的GSH能有效切斷雙硫鍵，使得熒光分子熒光增強(qiáng)，而*則用于殺死癌細(xì)胞，能同時(shí)實(shí)現(xiàn)靶向送藥和可視化檢測療效等多重目的。

西安瑞禧生物科技有限公司400種熒光相關(guān)產(chǎn)品列表：

CY3 

CY5 

CY7 

CY3-NHS   Cy3 NHS Ester

CY5-NHS   Cy5 NHS Ester

CY7-NHS   Cy7 NHS Ester

CY3-N3

CY5-N3

CY7-N3

CY3-MAL

CY5-MAL

CY7-MAL

CY3-COOH

CY5-COOH

CY7-COOH

DSPE-PEG-CY5 

DSPE-PEG-CY7  

FITC-PEG-NH2

FITC-PEG-COOH

FITC-PEG-MAL

FITC-PEG-NHS

FITC-PEG-Biotin

RB-PEG-NH2

RB-PEG-COOH

RB-PEG-MAL

RB-PEG-NHS

RB-PEG-Biotin

CY3-PEG-NH2

CY3-PEG-COOH

CY3-PEG-MAL

CY3-PEG-NHS

CY3-PEG-Biotin

CY5-PEG-NH2

CY5-PEG-COOH

CY5-PEG-MAL

CY5-PEG-NHS

CY5-PEG-Biotin

FITC-Poly-L-lysine

FITC-PLL

FITC-dextran

FITC-CM-dextran

TRITC-dextran

BSA-FITC

BSA-TRITC

FITC-Hyaluronic acid

BSA-FITC

Concanavalin A-CY5

Concanavalin A-Biotin

Concanavalin A-SH

Concanavalin A-TRITC

Streptavidin-SH

FITC-Streptavidin

CY5.5-Streptavidin

CY5-Streptavidin

HSA-FITC

HSA-TRITC

HSA-Biotin

BSA-TRITC

Concanavalin A-Sepharose

Concanavalin A-CY3

Avidin-CY3

Avidin-CY5

Avidin-CY5.5

Avidin

Avidin-Sepharose

Avidin-thiol

Avidin-FITC

Avidin-TRITC

Rhodamine B-Hyaluronic acid

6-Carboxy Fluorescein; 6-FAM

5(6)Carboxy fluorescein; 5(6)-FAM

5-Carboxyfluorescein succinimidyl ester; 5-FAM, SE

5-Carboxytetramethylrhodamine; 5-TAMRA

5(6)-Carboxytetramethylrhodamine succinimidyl ester;5(6)-TAMRA, SE

5-Carboxy-X-rhodamine; 5-ROX

6-Carboxy-X-rhodamine; 6-ROX

5(6)-Carboxy-X-rhodamine; 5(6)-ROX

5(6)-Aminofluorescein

5(6)-Carboxyfluorescein diacetate

5-Aminofluorescein

Fluorescein isothiocyanate

AMCA Alkyne

AMCA Azide

DBCO-Cy3

DBCO-Cy5

5-FAM Alkyne

5-FAM Azide

6-Carboxy-X-Rhodamine，SE (NHS) 6-羧基-X-羅丹明琥珀酰亞胺酯

5-TAMRA-Osu   5-羧基四甲基羅丹明琥珀酰亞胺酯

Streptavidin-CY5.5

Streptavidin-CY5

Streptavidin-CY3

Streptavidin-TRITC

Streptavidin-FITC

Streptavidin-thiol

Avidin-CY3

Avidin-CY5

Avidin-CY5.5

Avidin (without modification) 

Avidin-Sepharose

Avidin-thiol

Avidin-FITC

Avidin-TRITC

Human serum albumin, Sepharose beads （HAS- Sepharose beads）

Human serum albumin thiol (HSA-SH)

Human serum albumin Biotin (HSA-Biotin)

Human serum albumin TRITC (HSA-TRITC)

Human serum albumin Fluorescein (HSA-FITC)

Human serum albumin CY5 (HSA-CY5)

Human serum albumin CY3 (HSA-CY3)

Human serum albumin CY5.5 (HSA-CY5.5)

Human serum albumin (HSA, without modification)

Bovine serum albumin, Sepharose beads （BSA- Sepharose beads）

Bovine serum albumin thiol (BSA-SH)

Bovine serum albumin Biotin (BSA-Biotin)

Bovine serum albumin TRITC (BSA-TRITC)

Bovine serum albumin Fluorescein (BSA-FITC)

Bovine serum albumin CY5 (BSA-CY5)

Bovine serum albumin CY3 (BSA-CY3)

Bovine serum albumin CY5.5 (BSA-CY5.5)

Bovine serum albumin (BSA, without modification)

Bovine serum albumin tetramethylrhodamine (BSA-tetramethylrhodamine)

Concanavalin A刀豆求蛋白A產(chǎn)品：

Concanavalin A-CY5

Concanavalin A-CY3

Concanavalin A-CY5.5

Concanavalin A-Sepharose

Concanavalin A-Biotin

Concanavalin A-SH

Concanavalin A-tetramethylrhodamine

Concanavalin A-FITC

Concanavalin A (without modification)

Ficoll-Fluorescein, MW 20 kDa

Ficoll-Fluorescein, MW 40 kDa

Ficoll-Fluorescein, MW 70 kDa

Ficoll-Fluorescein, MW 400 kDa

Heparin-Biotin, MW 18 kDa

Heparin-Rhodamine, MW 18 kDa

Heparin-Fluorescein, MW 18 kDa

Heparin-NIR Dye, HP MW: 18kDa

Heparin-Amine, MW 18 kDa

Chitosan-Rhodamine, 200-500 cP, 85% DDA

Chitosan-Rhodamine, MW 200kDa, 95% DDA

Chitosan-Rhodamine, MW 200kDa, 85% DDA

Chitosan-Fluorescein, 10-50 cP, 85% DDA

Chitosan-Fluorescein, 200-500 cP, 85% DDA

Chitosan-Fluorescein, MW 200kDa, 95% DDA

Chitosan-Fluorescein, MW 200kDa, 85% DDA

Dextran-Biotin, MW 6 kDa

Dextran-Biotin, MW 20 kDa

Dextran-Biotin, MW 40 kDa

Dextran-Biotin, MW 70 kDa

Dextran-Biotin, MW 100 kDa

Dextran-Biotin, MW 550 kDa

Dextran-Biotin, MW 2,000 kDa

Dextran-Rhodamine, MW 6 kDa

Dextran-Rhodamine, MW 20 kDa

Dextran-Rhodamine, MW 40 kDa

Dextran-Rhodamine, MW 70 kDa

Dextran-Rhodamine, MW 100 kDa

Dextran-Rhodamine, MW 550 kDa

Dextran-Rhodamine, MW 2,000 kDa

Dextran-Fluorescein, MW 6 kDa

Dextran-Fluorescein, MW 20 kDa

Dextran-Fluorescein, MW 40 kDa

Dextran-Fluorescein, MW 70 kDa

Dextran-Fluorescein, MW 100 kDa

Dextran-Fluorescein, MW 550 kDa

Dextran-Fluorescein, MW 2,000 kDa

Dextran-NIR Dye, DE MW: 6k-2000k

Dextran-Amine, MW 6 kDa

Dextran-Amine, MW 20 kDa

Dextran-Amine, MW 40 kDa

Dextran-Amine, MW 70 kDa

Dextran-Amine, MW 100 kDa

Dextran-Amine, MW 550 kDa

Dextran-Amine, MW 2,000 kDa

FITC-DEAE-dextrans熒光素葡聚糖產(chǎn)品：

FITC-DEAE-dextran,MW:3000-6000

FITC-DEAE-dextran,MW:20000-30000

FITC-DEAE-dextran,MW:30000-60000

FITC-DEAE-dextran,MW:70000-90000

FITC-DEAE-dextran,MW:160000-190000

FITC-Inulin熒光素菊粉產(chǎn)品：

FITC-Inulin,MW:4000

FITC-Polysucrose熒光素聚蔗糖產(chǎn)品：

FITC-Polysucrose,MW:15000-30000

FITC-Polysucrose,MW:30000-50000

FITC-Polysucrose,MW:70000

FITC-Polysucrose,MW:300000-450000

FITC-CM-Polysucrose 熒光素羧基聚蔗糖產(chǎn)品：

FITC-CM-Polysucrose,MW:60000-80000

FITC-CM-Polysucrose,MW:350000-450000

FITC-DEAE-Polysucrose熒光素DEAE聚蔗糖產(chǎn)品：

FITC-DEAE-Polysucrose,MW:400000

FITC-Dextran sulfate產(chǎn)品：

FITC-Dextran sulphate,MW:30000-50000

FITC-Dextran sulphate,MW:400000-650000

CY3-Dextran, CY5-Dextran，CY7-Dextran產(chǎn)品列表：

DX5-S3-1      Dextran, Cy3 labeled     5000 Da     2 mg 

DX10-S3-1     Dextran, Cy3 labeled     10000 Da         5 mg 

DX40-S3-1     Dextran, Cy3 labeled     40000 Da   5 mg

Thiol Dextran產(chǎn)品列表:

DX5-TH-1      Dextran, Thiol Functional     5000 Da  50 mg    

DX10-TH-1    Dextran, Thiol Functional     10000 Da       50 mg    

DX40-TH-1    Dextran, Thiol Functional     40000 Da       50 mg    

Wheat germ agglutinin & Conjugates（麥胚凝集素交聯(lián)劑）

FITC-Wheat germ agglutinin

RB-Wheat germ agglutinin

CY3-Wheat germ agglutinin

CY5-Wheat germ agglutinin

Transferrin & Conjugates（熒光標(biāo)記轉(zhuǎn)染鐵蛋白）

FITC-Transferrin

RB-Transferrin

CY3-Transferrin

CY5-Transferrin

CY7-Transferrin

Biotin-Transferrin

Lysozyme & conjugates（熒光標(biāo)記*）

FITC-Lysozyme

RB-Lysozyme

CY3-Lysozyme

CY5-Lysozyme

CY7-Lysozyme

Biotin-Lysozyme

Catalase conjugates（熒光標(biāo)記過氧化氫酶）

FITC-Catalase

RB-Catalase

CY3-Catalase

CY5-Catalase

CY7-Catalase

Biotin-Catalase

Polylysine conjugates（熒光標(biāo)記多聚賴氨酸氨酸）

FITC-Polylysine

RB-Polylysine

CY3-Polylysine

CY5-Polylysine

CY7-Polylysine

Biotin-Polylysine

Protein A & conjugates（熒光標(biāo)記蛋白A）

FITC-Protein A

RB-Protein A

CY3-Protein A

CY5-Protein A

CY7-Protein A

Biotin-Protein A

HRP-Protein A

Maleimide-Protein A

Insulin & conjugates(熒光標(biāo)記胰島素)

FITC-Insulin

RB-Insulin

CY3-Insulin

CY5-Insulin

Biotin-Insulin

Horseradish Peroxidase (HRP) Conjugates（辣根過氧化物酶交聯(lián)劑）

Biotin-HRP

Streptavidin-HRP

FITC-HRP

CY3-HRP

CY5-HRP

RB-HRP

Maleimide-HRP

NH2-HRP

HS-HRP

Hylauronic acid & Conjugates（透明質(zhì)酸交聯(lián)劑）

FITC-Hylauronic acid

RB-Hylauronic acid

CY3-Hylauronic acid

CY5-Hylauronic acid

CY7-Hylauronic acid

Biotin-Hylauronic acid

Heparin & Conjugates（肝素交聯(lián)劑）

FITC-Heparin

RB-Heparin

CY3-Heparin

CY5-Heparin

Biotin-Heparin

Ficoll & Conjugates（聚蔗糖交聯(lián)劑）

FITC-Ficoll

RB-Ficoll

CY3-Ficoll

CY5-Ficoll

Biotin-Ficoll

Chitosan & Conjugates（殼聚糖交聯(lián)劑）

FITC-Chitosan

RB-Chitosan

CY3-Chitosan

CY5-Chitosan

Biotin-Chitosan

Lipopolysaccharides Conjugates（脂多糖交聯(lián)）

FITC-Lipopolysaccharides

RB-Lipopolysaccharides

CY3-Lipopolysaccharides

CY5-Lipopolysaccharides

CY5.5-Lipopolysaccharides

Casein conjugates（酪蛋白交聯(lián)劑）

FITC-Casein

RB-Casein

CY3-Casein

CY5-Casein

CY5.5-Casein

Biotin-Casein

α-Chymotrypsin conjugates （α-胰凝乳蛋白交聯(lián)劑）

FITC-α-Chymotrypsin

RB-α-Chymotrypsin

CY3-α-Chymotrypsin

CY5-α-Chymotrypsin

CY5.5-α-Chymotrypsin

Polylysine & conjugates（多聚賴氨酸和共軛物）

FITC-Polylysine

RB-Polylysine

CY3-Polylysine

CY5-Polylysine

CY5.5-Polylysine

Biotin-Polylysine

C10B0            Cyanine3 alkyne, 10 mg

C1030            Cyanine3 azide, 10 mg

21090             Cyanine3 carboxylic acid, 5 mg

21070             Cyanine3 hydrazide, 5 mg

21080             Cyanine3 maleimide, 5 mg

21020             Cyanine3 NHS ester, 5 mg

41020             Cyanine3 NHS ester, 25 mg

B2030            Cyanine3.5 azide, 5 mg

42090             Cyanine3.5 carboxylic acid, 25 mg

52020             Cyanine3.5 NHS ester, 50 mg

B30B0            Cyanine5 alkyne, 5 mg

230C0            Cyanine5 amine, 5 mg

C3030            Cyanine5 azide, 10 mg

430A0            Cyanine5 Boc-hydrazide, 25 mg

43090             Cyanine5 carboxylic acid, 25 mg

23070             Cyanine5 hydrazide, 5 mg

43080             Cyanine5 maleimide, 25 mg

23020             Cyanine5 NHS ester, 5 mg

B70B0            Cyanine5.5 alkyne, 5 mg

B4030            Cyanine5.5 azide, 5 mg

27090             Cyanine5.5 carboxylic acid, 5 mg

57080             Cyanine5.5 maleimide, 50 mg

27020             Cyanine5.5 NHS ester, 5 mg

450C0            Cyanine7 amine, 25 mg

B5030            Cyanine7 azide, 5 mg

45090             Cyanine7 carboxylic acid, 25 mg

25080             Cyanine7 maleimide, 5 mg

25020             Cyanine7 NHS ester, 5 mg

260C0            Cyanine7.5 amine, 5 mg

B6030            Cyanine7.5 azide, 5 mg

26090             Cyanine7.5 carboxylic acid, 5 mg

26080             Cyanine7.5 maleimide, 5 mg

26020             Cyanine7.5 NHS ester, 5 mg

23320             Sulfo-Cyanine 5 NHS ester, 5 mg

B1330            Sulfo-Cyanine3 azide, 5 mg

21390             Sulfo-Cyanine3 carboxylic acid, 5 mg

21380             Sulfo-Cyanine3 maleimide, 5 mg

21320             Sulfo-Cyanine3 NHS ester, 5 mg

B33B0            Sulfo-Cyanine5 alkyne, 5 mg

B3330            Sulfo-Cyanine5 azide, 5 mg

23390             Sulfo-Cyanine5 carboxylic acid, 5 mg

23380             Sulfo-Cyanine5 maleimide, 5 mg

B5330            Sulfo-Cyanine7 azide, 5 mg

25390             Sulfo-Cyanine7 carboxylic acid, 5 mg

45320             Sulfo-Cyanine7 NHS ester, 25 mg