| 英文名稱 | Mouse IgA |
| 中文名稱 | 兔抗小鼠IgA抗體 |
| 別 名 | A2m marker; FLJ14473; FLJ35065; FLJ35500; FLJ36402; FLJ39698; FLJ40001; FLJ41548; FLJ41552; FLJ41789; FLJ43248; FLJ43594; FLJ44293; FLJ46028; FLJ46621; FLJ46724; FLJ46811; FLJ46824; Ig alpha 1 chain C region; Ig alpha 2 chain C region; IgA1; Igh2; IGHA 1; IGHA 2; IGHA1; IGHA2; Immunoglobulin alpha 1; Immunoglobulin Am1; Immunoglobulin Am2; Immunoglobulin heavy chain 2 (serum IgA); Immunoglobulin heavy constant alpha 1; Immunoglobulin heavy constant alpha 2; MGC102857. |
| 說(shuō) 明 書(shū) | 0.2ml |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, |
| 產(chǎn)品應(yīng)用 | ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 55kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/1ml |
| 免 疫 原 | Mouse IgA protein purified |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A from plasma |
| 儲(chǔ) 存 液 | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | background: Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA. OR: The secretory component is a component of immunoglobulin A (IgA) which consists of a portion of the polymeric immunoglobulin receptor. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell via transcytosis. The receptor-IgA complex passes through the cellular compartments before being secreted on the luminal surface of the epithelial cells, still attached to the receptor. Proteolysis of the receptor occurs and the dimeric IgA molecule, along with the secretory component, are free to diffuse throughout the lumen. |
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