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Anti-Human CD19 PE and CD5 FITC Cocktail

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產(chǎn)品型號FITC

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更新時間：2017-12-30 04:32:34瀏覽次數(shù)：313次

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上海經(jīng)科化學科技有限公司

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商鋪產(chǎn)品：183條

所在地區(qū)：上海上海市

聯(lián)系人：李小姐

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產(chǎn)品簡介

Reactivity Human
Conjugate FITC
Laser Blue Laser
Emit N/A
Excite N/A
Reported Applications Flow Cytometric Analysis

詳細介紹

Description: This product consists of two fluorochrome-conjugated monoclonal antibodies to distinguish human peripheral CD5⁺ T cells and CD19⁺ B cells. The UCHT2 monoclonal antibody （mouse IgG1, κ, HLDA # III518） reacts with human CD5, a 67 kDa protein expressed by the majority of thymocytes and mature T cells and a subset of B cells. Signaling through the CD5 molecule activates T cells and binding of CD5 to its ligand on B cells, CD72, and plays an important role in T-B interaction and proliferation. The HIB19 monoclonal antibody （mouse IgG1, κ, HLDA # V CD19.11） reacts with human CD19, a 95 kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together CD21, CD81, Leu13, MHC class II, and CD19 form a multimolecular complex that associates with BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells.