產(chǎn)品名稱：Anti-MTG1/GTPBP7抗體,GTP結(jié)合蛋白7抗體

產(chǎn)品編號(hào)：BYK-17874R
英文名稱：Anti-MTG1/GTPBP7
中文名稱：GTP結(jié)合蛋白7抗體
英文別名：GTP;

GTP binding protein;

GTP binding protein 7 (putative);

GTP binding protein 7;

GTP-binding protein 7 (putative);

GTP-binding protein 7;

GTPBP7;

Mitochondrial GTPase 1;

mitochondrial GTPase 1 homolog (S. cerevisiae);

MTG1;

MTG1_HUMAN;

OTTHUMP00000020814;

OTTHUMP00000046565;

RP11 108K14.2;

RP11-108K14.2;

RP11108K14.2.
英文介紹：MTH1 is a 179 amino acid cytoplasmic protein that is a member of the nudix hydrolase family. Highly expressed in testis, thymus and proliferating blood lymphocytes, MTH1 functions as an antimutagenic that hydrolyzes oxidized purine nucleoside triphosphates to their corresponding monophosphates. Through its ability to enzymatically hydrolyze ATP and GTP to AMP and GMP, respectively, MTH1 prevents misincorporation of GTP into DNA, thus preventing A:T to C:G transversions. The cytoplasmic location of MTH1, along with its antimutagenic capabilities, suggests that it may also be involved in the sanitization of nucleotide pools for both mitochondrial and nuclear genomes. Four isoforms of MTH1 exist—three of which are formed due to alternative splicing events and one of which is formed via a single-nucleotide polymorphism. Overexpression of MTH1 is implicated in prostate and cell lung carcinomas

產(chǎn)品規(guī)格：0.1ml/0.2ml

注意事項(xiàng):This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯(lián)免疫(ELISA)，IF、IP、流式細(xì)胞術(shù)等實(shí)驗(yàn)（可來(lái)電索取說(shuō)明）
此產(chǎn)品本公司有標(biāo)記的一抗出售，相關(guān)標(biāo)記有：Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記

保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-MTG1/GTPBP7抗體,GTP結(jié)合蛋白7抗體免疫組化操作流程
1 脫蠟和水化：脫蠟前應(yīng)將組織芯片在室溫中放置60分鐘或60℃恒溫箱中烘烤20分鐘。 a 組織芯片置于二甲苯中浸泡10分鐘,更換二甲苯后在浸泡10分鐘
b 無(wú)水乙醇中浸泡五分鐘
c 95%乙醇中浸泡五分鐘
d 75%乙醇中浸泡五分鐘
2 抗原修復(fù)：用于福爾馬林固定的石蠟包埋組織芯片：
A 抗原熱修復(fù)
a 高壓熱修復(fù) 在沸水中加入EDTA（ph8.0）或0.01m*緩沖溶液（ph6.0）.蓋上不銹鋼鍋蓋，但不能鎖定。將玻片置于金屬染色加上，緩慢加壓，是玻片在緩沖液中浸泡五分鐘，然后將蓋子鎖定，小閥門(mén)將會(huì)升起來(lái)。10分鐘后除去熱源，置入涼水中，當(dāng)小閥門(mén)沉下去后打開(kāi)蓋子。此方法適用于較難檢測(cè)或核抗原的抗原修復(fù)。
b 沸熱修復(fù) 電爐或水浴鍋加熱0.01*緩沖液（ph6.0）至95℃左右，放入組織芯片加熱10-15分鐘。
C 微波爐加熱 在微波爐里加熱0.01*緩沖液（ph6.0）至沸騰后將組織芯片放入，斷電，間隔5-10分鐘，反復(fù)1-2次。適用的抗原：
Bcl-2.Bax.AR.PR.C-fos.x-jum.z-kit.c-myc.E-cadherin.
ChromograninA.Cyclin.ER.Heatshock.Protein.HPV.Ki-67.MDMZ.P53.P34.P15.P-glycoprotein.PKC.PCNA.ras.Rb.等
B 酶消化方法 
常用0.1%*和0.4%*液。*使用前預(yù)熱37℃，消化時(shí)間約為5-30分鐘。適用于被固定遮蔽的抗原：包括 Collagen.GFAP.
Complement.Cytokeratin.C-erB-2.LCA.LN.等

Anti-MTG1/GTPBP7抗體,GTP結(jié)合蛋白7抗體其他優(yōu)勢(shì)產(chǎn)品：

byk-0447R 甲狀腺過(guò)氧化物酶抗體 Anti-Thyroid peroxidase
byk-1215R *羥化酶抗體 Anti-TPH
byk-11215R 神經(jīng)叢蛋白B2抗體 Anti-Plexin B2
byk-1203R DNA拓普西異構(gòu)酶Ⅱ抗體 Anti-TOPO II/TOPO II Alpha
byk-11203R 八聚體結(jié)合轉(zhuǎn)錄因子6抗體 Anti-OCT6
byk-1920R DNA拓普西異構(gòu)酶ⅡA抗體 Anti-TOP2 alpha
byk-11920R 螺旋轉(zhuǎn)錄因子OTP抗體 Anti-OTP
byk-1211R 線粒體DNA拓普西異構(gòu)酶Ⅰ抗體 Anti-*mt/TOPO Ⅰ
byk-11211R 驅(qū)動(dòng)蛋白家族蛋白3抗體 Anti-KIF3A
byk-2457R 腫瘤壞死因子受體超家族成員14抗體 Anti-TNFRSF14/HVEM
byk-2456R 腫瘤壞死因子配體超家族成員18抗體 Anti-TNFSF18
byk-12456R 磷酸化蛋白激酶AKT1抗體 Anti-phospho-AKT1 (Ser473)
byk-0905R 乙酰化P53(Lys382)抗體 Anti-Acetyl-p53(K382)
byk-12462R 衰老相關(guān)蛋白5抗體 Anti-AGPS
byk-2104R 腫瘤壞死因子α誘導(dǎo)蛋白1抗體 Anti-TNFAIP1
byk-12104R 突觸富含*膜蛋白7抗體 Anti-PRR7
byk-0093R 腫瘤壞死因子β抗體（TNFβ） Anti-TNF beta
byk-10093R 白細(xì)胞抗原CD97 alpha 抗體 Anti-CD97 antigen subunit alpha
byk-2685R CD134抗體 Anti-TNFRSF4/OX40/CD134
byk-2463R 腫瘤壞死因子配體超家族成員4抗體 Anti-TNFSF4/CD252
byk-12463R 磷酸化熱休克蛋白β5/αb晶體蛋白質(zhì)/α-晶體蛋白b鏈抗體 Anti-phospho-alpha B Crystallin (Ser59)
byk-0078R 腫瘤壞死因子-α/TNFα抗體 Anti-TNF alpha

咨詢及訂購(gòu)的方法：
1.可來(lái)電向我們直接咨詢及訂購(gòu)。：021-6034 0820,158 0061 4926
2.可加客服或交談，向我司在線人員咨詢及訂購(gòu)。
3.可通過(guò)郵件咨詢及訂購(gòu)。