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產(chǎn)品名稱：Anti-DOPA Decarboxylase/FITC,FITC標(biāo)記的多巴胺脫羧酶抗體
產(chǎn)品編號：BYK-0180R-FITC
英文名稱 Anti-DOPA Decarboxylase/FITC
中文名稱 FITC標(biāo)記的多巴胺脫羧酶抗體
別名 AADC; DDC; Aromatic L Amino Acid Decarboxylase; DDC protein; DOPA decarboxylase; aromatic-L-amino-acid decarboxylase isoform 1; DDC_HUMAN.
研究領(lǐng)域 神經(jīng)生物學(xué)
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDC
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-DOPA Decarboxylase/FITC,FITC標(biāo)記的多巴胺脫羧酶抗體產(chǎn)品介紹：DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.
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