Anti-AKR1C3抗體,實驗方法醛固酮還原酶家族1成員C3抗體抗體應用于WB、IHC、IF、ELISA等實驗中，產品貨期快、質量品牌保障，并提供完善的售前、售中、售后服務！咨詢或在線客服！我們將竭誠為您服務！公司堅持對產品質量作不斷的評估、創(chuàng)新和改善以確保您對我們產品的高度信任！
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英文名稱 AKR1C3
中文名稱 Anti-AKR1C3抗體,實驗方法醛固酮還原酶家族1成員C3抗體
別    名 17 beta HSD 5; 17 beta hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 17-beta-hydroxysteroid dehydrogenase type 5; 2-dihydrobenzene-1; 2-diol dehydrogenase; 3 alpha hydroxysteroid dehydrogenase type II; 3-alpha-HSD type 2; 3-alpha-HSD type II; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; AK1C3_HUMAN; AKR1 C3; AKR1C3; Aldo keto reductase family 1 member C3; Aldo-keto reductase family 1 member C3; brain; Chlordecone reductase; Chlordecone reductase homolog HAKRb; DD-3; DD3; DDH1; DDX; Dihydrodiol dehydrogenase 3; Dihydrodiol dehydrogenase type I; Dihydrodiol dehydrogenase X; HA1753; HAKRB; HAKRe; hluPGFS; HSD17B5; Indanol dehydrogenase; KIAA0119; PGFS; Prostaglandin F synthase; Testosterone 17-beta-dehydrogenase 5; Trans-1; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Type IIb 3 alpha hydroxysteroid dehydrogenase.  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  內分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Dog, Pig, Cow, Horse, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AKR1C3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

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產品介紹 DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol. ?Human liver contains isoforms of dihydrodiol dehydrogenase (DD1, DD2, DD3 and DD4), which belong to the aldo-oxo reductase/aldo-keto reductase (AKR) superfamily, have 20Alpha- or 3Alpha-hydroxysteroid dehydrogenase (HSD) activity. DD1 is also designated AKR1C1, DDH or DDH1 while DD2 also can be designated AKR1C2, dDD, BABP or DDH2. AKR1C3 and 3Alpha-HSD are alternate designations for DD3, while DD4 also can be called AKR1C4, CD or CHDR. DD1 and DD2 are 20Alpha-HSDs, whereas DD3 and DD4 are the 3Alpha-HSDs. The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, such as polycyclic aromatic hydrocarbons, pesticides and steroid hormones, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor. The 20Alpha-HSD catalyzes the reaction of progesterone to the inactive form 20Alpha-hydroxyprogesterone. The 3Alpha-HSD is a cytosolic, monomeric, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products. DD1 and DD2 are ubiquitously expressed, whereas DD4 mRNA is restricted to the liver.
醛固酮還原酶家族1成員C3抗體儲存溫度：存在于血清、組織培養(yǎng)上清液或腹水中的抗體在-20℃下能夠*儲存。低溫存放不會損傷抗體活性。抗體的工作液通常儲存于4℃中。此溫度下，抗體的活性能穩(wěn)定數(shù)月至數(shù)年亦不損失?？贵w溶液不應反復凍融，因為反復凍融將導致部分抗體失活并產生不需要的蛋白—蛋白凝聚物?？贵w的凝聚能導致活性喪失。這是由于抗原結合位點的空間構象被破壞，或由于產生的不溶物被離心或過濾而除去。冷凝蛋白類的抗體不能存放于4℃。因為在4℃下此類抗體會發(fā)生沉淀。一些鼠源性IgG3亞類的抗體有此特性。如果抗體在4℃下發(fā)生沉淀，就應該存放于室溫下的疊氮鈉溶液中。
保存條件：低溫
運輸：4度，或干冰。
公司抗體具有高純度、高效價、高特異性的特點，僅用于科學研究，不可用于臨床診斷及藥物治療，可以應用于多種實驗。