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聯(lián)系我時(shí)，請(qǐng)告知來自 環(huán)保在線NFE2L2ProteinD77Vmutant[10446][100ul]CatalogNumber:10446ProductName:NFE2L2ProteinD77VmutantSynonyms:Nuclearfactor(erythroid-derived2)-like2
NFE2L2 Protein D77V mutant [10446]
[100ul]
| Catalog Number: 10446 |
| Product Name: NFE2L2 Protein D77V mutant |
| Synonyms: Nuclear factor (erythroid-derived 2)-like 2, Nrf2 |
| Source: Human, recombinant full length, His6-tag |
| Expression Host: E. coli |
| Molecular Weight: 26 kDa |
| Purity: >99% by SDS-PAGE |
| Introduction: NFE2L2 protein is encoded by NFE2L2 gene. It is a basic leucine zipper protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. Several drugs that stimulate the NFE2L2 pathway are being studied for treatment of diseases that are caused by oxidative stress. |
| Amino Acid Sequence (1-170) |
| MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFD FSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL VEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDAL YFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIE SPVFIATNQAQSPETSVA |
| Properties |
| Physical Appearance (form): Dissolved in 20mM Tris-HCl, pH8.0, 150mM NaCl. |
| Physical Appearance (form): White or clear |
| Concentration: 1 mg/mL |
| Storage: -80°C |
| Preparation Instructions: Adding of 10 mM β-mercaptoethanol or 1 mM DTT into the solution to protect the protein is recommended and using of non-ionic detergents such as n-Dodecyl β-D-maltoside (DoDM) or polyethylene detergents (e.g. C12E10) also help to stabilize the protein. Avoid repeated freezing and thawing. The purity of His-tagged NFE2L2 D77V was determined by SDS-PAGE and Coomassie Brilliant Blue Staining. |
| References: 1. Moi P et al., Proc. Natl. Acad. Sci. U.S.A. 91 (21): 9926-30. 2. Gold R et al., N. Engl. J. Med. 367 (12): 1098-107. |
| Datasheet: |
| Related Products | |||
| Catalog# | Name | Size | Price |
| Anti NFE2L2 Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
| Anti NFE2L2(E79K) Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
| Anti NFE2L2(D29G) Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
| Anti NFE2L2(E79Q) Mouse Monoclonal Antibody | 100 μL | ￥4800 | |
| Anti NFE2L2(L30F) Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
| Anti NFE2L2(D77V) Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
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