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Angiotensin II (human), [125I]-Tyr4, 10 μCi

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珀金埃爾默醫(yī)學(xué)診斷產(chǎn)品（上海）有限公司

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產(chǎn)品簡介

Angiotensin II (human), labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin II binds and activates angiotensin II receptor type 1 (AT1) and type 2 (AT2) receptors, a class of GPCRs important......

詳細(xì)介紹

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligａnd binding assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New Englａnd Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX105:

Oppermann, M., Gess, B., Schweda, F., and Castrop, H. (2009), Atrap Deficiency Increases Arterial Blood Pressure and Plasma Volume. JASN, 21 (3): 468-477.

規(guī)格

檢測(cè)方法	Radiometric
產(chǎn)品品牌名稱	NEN Radiochemicals
放射性同位素	125I
運(yùn)輸條件	環(huán)境
產(chǎn)品尺寸	10 µCi