Anti-Progestin Receptor Beta抗體,說明書孕激素受體β（MPRβ）抗體抗體應(yīng)用于WB、IHC、IF、ELISA等實驗中，產(chǎn)品貨期快、質(zhì)量品牌保障，并提供完善的售前、售中、售后服務(wù)！咨詢或在線客服！我們將竭誠為您服務(wù)！公司堅持對產(chǎn)品質(zhì)量作不斷的評估、創(chuàng)新和改善以確保您對我們產(chǎn)品的高度信任！
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英文名稱 Progestin Receptor Beta
抗體名稱 Anti-Progestin Receptor Beta抗體,說明書孕激素受體β（MPRβ）抗體
別    名 MPRB; C6orf33; LMPB1; Lysosomal membrane protein in brain 1; Membrane progestin receptor beta; mPR beta; MPRB; PAQR8; Progestin and adipoQ receptor family member 8; Progestin and adipoQ receptor family member VIII; MPRB_HUMAN.  
研究領(lǐng)域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Progestin Receptor Beta (251-300aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

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Anti-Progestin Receptor Beta抗體,說明書孕激素受體β（MPRβ）抗體產(chǎn)品介紹 The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Five distinct groups, designated Alpha, Beta, Gamma, Delta, comprise the mPR gene family. mPR Alpha, also designated progestin and adipo Theta receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus and seven transmembrane domains. mPR Alpha is expressed in ovary, testis, placenta, uterus and bladder. mPR Beta, or progestin and adipo Theta receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. mPR Beta is a 354 amino acid protein expressed in brain and spinal cord. Both mPR Alpha and mPR Beta may be G protein-coupled receptors and may be involved in oocyte maturation.
孕激素受體β（MPRβ）抗體儲存溫度：存在于血清、組織培養(yǎng)上清液或腹水中的抗體在-20℃下能夠*儲存。低溫存放不會損傷抗體活性?？贵w的工作液通常儲存于4℃中。此溫度下，抗體的活性能穩(wěn)定數(shù)月至數(shù)年亦不損失。抗體溶液不應(yīng)反復凍融，因為反復凍融將導致部分抗體失活并產(chǎn)生不需要的蛋白—蛋白凝聚物。抗體的凝聚能導致活性喪失。這是由于抗原結(jié)合位點的空間構(gòu)象被破壞，或由于產(chǎn)生的不溶物被離心或過濾而除去。冷凝蛋白類的抗體不能存放于4℃。因為在4℃下此類抗體會發(fā)生沉淀。一些鼠源性IgG3亞類的抗體有此特性。如果抗體在4℃下發(fā)生沉淀，就應(yīng)該存放于室溫下的疊氮鈉溶液中。
保存條件：低溫
運輸：4度，或干冰。
公司抗體具有高純度、高效價、高特異性的特點，僅用于科學研究，不可用于臨床診斷及藥物治療，可以應(yīng)用于多種實驗。