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Anti PIK3CA(E542K) Mouse Monoclonal Antibody

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參   考   價: 4800

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PIK3CA(E542K)[26234][100ul]CatalogNumber:26234GeneSymbol:PIK3CA

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PIK3CA(E542K) [26234]
[100ul]


Catalog Number:  26234
Gene Symbol:  PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Description:   Anti PIK3CA(E542K) Mouse Monoclonal Antibody
Background:   Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found in the pathogenesis of several cancers, including colon cancer, gliomas, gastric cancer, breast cancer, endometrial cancer, and lung cancer.
Immunogen:   A synthetic peptide from the internal region of PIK3CA which includes the mutation of E542K, human origin.
Applications:   ELISA, WB
Recommended Dilutions:   
ELISA: 1:1000-1:5000 
WB: 1:500-1:2000
Concentration:   1 mg/ml
Host:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes E542K mutant, but not wild-type PIK3CA of vertebrates.
Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
Download Datasheet:  
Western blot:  
Western blot analysis of recombinant PIK3CA(E542K) and wildtype proteins. Purified His-tagged PIK3CA(E542K) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti PIK3CA(E542K) monoclonal antibody (Cat. #26234).


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